Upcoming Webinar: Cognitive Dysfunction Syndrome in Cats
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Join Dr Sagi Denenberg DVM MRCVS CCAB DipACVB DipECAWBM as he presents on the fascinating topic of Cognitive Dysfunction Syndrome in Cats. Time/Date: 9:30am (AEST) Wednesday 8 April 2026 Fees
Note: A 3.5% PayPal Surcharge Fee applies to all registrations. If you are a Resident, contact EducationVetBehaviour@anzcvs.org.au for the discount code. Synopsis: Feline cognitive dysfunction syndrome is a progressive neurodegenerative condition in senior cats, typically appearing around or after ten years of age. It is characterised by declining cognitive performance and behavioural changes that cannot be fully explained by other medical conditions. Because many signs overlap with common geriatric ailments, such as chronic pain or sensory decline, it is considered a diagnosis of exclusion. Clinicians identify the syndrome using the VISHDAAL framework, which tracks changes in vocalisation, social interactions, sleep-wake cycles, house-soiling, disorientation, activity levels, anxiety, and learning or memory. Owners often misattribute these early shifts to normal ageing, which frequently delays professional intervention. The underlying pathophysiology involves a convergence of protein abnormalities, such as amyloid-β and tau, alongside neuroinflammation, oxidative injury, and cerebrovascular dysfunction. Management is multimodal and focused on improving quality of life rather than achieving a cure. The most effective strategy involves optimising the treatment of comorbidities like osteoarthritis, hypertension, and kidney disease, which can mimic or worsen cognitive signs. Environmental enrichment is also vital, involving the creation of a predictable environment with accessible resources like low-sided litter trays, ramps, and night lights. While nutritional support with antioxidants and Omega-3 fatty acids shows biological plausibility, pharmacological options remain largely extrapolated from canine data and require careful individualisation. |